1. Organising screening programmes
In the context of an organised screening programme, the ECIBC's Guidelines Development Group (GDG) suggests:
- using double reading (with consensus or arbitration for discordant readings) to screen mammograms for early detection of breast cancer (conditional recommendation, moderate certainty of the evidence)
- mammography readers read between 3 500 and 11 000 mammograms annually (conditional recommendation, very low certainty of the evidence)
Optimal number of mammography readings
Issued on: May 2019
Healthcare question
Should an optimal number of readings vs. no specific number be used for allowing mammography readers to work in mammography screening programmes?
Recommendation
The ECIBC's Guidelines Development Group (GDG) suggests that mammography readers read between 3 500 and 11 000 mammograms annually in organised population-based screening programmes.
Recommendation strength
| Conditional recommendation |
| Very low certainty of the evidence |
Justification
The right balance between sensitivity (true positives) and specificity (false positives) was found within the selected range of readings per reader.
Considerations for implementation and policy making
- This optimal range should be implemented as part of screening programmes that use double reading (which is a conditional recommendation previously issued), as double reading of mammograms will improve the overall quality of the reading.
- Efforts to provide support with centralised reading may help implementing this recommendation.
- The number of readings should be averages over longer periods and use appropriate sampling for this measurement.
- The GDG recognised that local circumstances of the individual's performance will affect the quality of readings as much as the number of readings.
- The suggested range applies to mammography screening, not tomosynthesis.
Monitoring and evaluation
Programmes should continue to monitor the number of readings by readers and the quality indicators of the reading process.
Research priorities
The GDG suggested the following research priorities:
- More published evidence is required which could also come from good monitoring data.
- Further research on elements that may influence results such as: when to read during the day, how many mammograms to read per day, time needed and variation of time for readings between readers, relationship between breast cancer detection and false positives, comparison between those reading only screening mammograms and those doing screening and clinical/diagnostic mammography.
- More research on types of training for mammography readers.
- Research into the role of artificial intelligence in double reading.
Supporting material
- Organised vs. non-organised screening
- Double vs. single reading in mammograpy screening
- Communication skills training
- Communication with care providers
- Optimal number of mammography readings
- Specialised training
- Risk stratification
- Women aged 40-44: screening vs. no screening
- Women aged 45-49: screening vs. no screening
- Women aged 45-49: annual vs. biennial screening
- Women aged 45-49: annual vs. triennial screening
- Women aged 45-49: triennial vs. biennial screening
- Women aged 50-69: screening vs. no screening
- Women aged 50-69: annual vs. biennial screening
- Women aged 50-69: annual vs. triennial screening
- Women aged 50-69: triennial vs. biennial screening
- Women aged 70-74: screening vs. no screening
- Women aged 70-74: annual vs. biennial screening
- Women aged 70-74: annual vs. triennial screening
- Women aged 70-74: triennial vs. biennial screening
- Single reading with AI support
- Double reading with AI support
- Screening with tomosynthesis vs. mammography
- Screening with tomosynthesis plus mammography vs. mammography alone
- Tailored screening with tomosynthesis
- Screening with tomosynthesis vs. mammography
- Tailored screening with MRI
- Tailored screening with ABUS
- Tailored screening with HHUS
- Informing about benefits and harms: use of decision aids
- Informing about benefits and harms: Numbers in addition to plain language
- Informing about benefits and harms: Infographics in addition to plain language
- Informing about benefits and harms: Story telling in addition to plain language
- Inviting women to screening: letter vs. no invitation
- Inviting socially disadvantaged women to screening: Targeted vs. general communication strategy
- Inviting women with an intellectual disability to screening
- Inviting non-native speakers to screening
- Inviting socially disadvantaged women to screening: Tailored vs. targeted communication strategy
- Inviting socially disadvantaged women to screening: Tailored vs. general communication strategy
- Inviting women to subsequent screening rounds: letter vs. no invitation
- Inviting women to screening: letter with fixed appointment vs. letter
- Inviting women to subsequent screening rounds: letter with fixed appointment vs. lett
- Inviting women to screening: letter with GP signature vs. letter
- Inviting women to subsequent screening rounds: letter with GP signature vs. letter
- Inviting women to screening: letter followed by phone call vs. letter
- Inviting women to subsequent screening rounds: letter followed by phone call vs. letter
- Inviting women to screening: letter followed by phone call vs. no invitation
- Inviting women to screening: letter followed by written reminder vs. letter
- Inviting women to subsequent screening rounds: letter followed by written reminder vs. letter
- Inviting women to screening: letter followed by face to face intervention vs. letter
- Inviting women to subsequent screening rounds: letter followed by face to face intervention vs. letter
- Inviting women to screening: e-mail vs. letter
- Inviting women to screening: automated telephone call vs. letter
- Inviting women to screening: letter followed by automated telephone call vs. letter
- Inviting women to screening: letter followed by SMS notification vs. letter
- Inviting women to screening: letter followed by personalised phone call vs. automated phone call
- Negative result: letter vs. nothing
- Further assessment: letter followed by a phone call
- Further assessment: timing of results
- Negative result: phone call vs. letter
- Negative result: face to face interview vs. letter
- Negative result: timing of results
- Tomosynthesis vs. assessment mammography
- Obtaining a sample from a suspicious breast lesion
- Type of guidance for needle core biopsy
- Stage 1: conventional exams
- Stage 1: PET-CT exams
- Stage 2: conventional exams
- Stage 2: PET-CT exams
- Stage 3: conventional exams
- Stage 3: PET-CT exams
- Stage 3: conventional exams plus PET-CT
- Use of clip-marking
- Additional magnetic resonance imaging
- Contrast-enhanced mammography
- Threshold of oestrogen for endocrine therapy
- Threshold of progesterone for endocrine therapy
- Multigene testing: 70 gene signature at low clinical risk
- Multigene testing: 70 gene signature at high clinical risk
- Multigene testing: 21 gene recurrence score
- Organising screening programmes
- Risk stratification
- Women 40-44
- Women 45-49
- Women 50-69
- Women 70-74
- Women with high breast density
- General Population
- Vulnerable Population
- Informing women about their results
- Women recalled due to suspicious lesions
- Obtaining a sample from a suspicious lesion
- Type of guidance for needle core biopsy
- Stage 1
- Stage 2
- Stage 3
- Planning surgical treatment
- Hormone receptor to guide use of endocrine therapy
- Multigene testing to guide use of chemotherapy